{"id":351152,"date":"2025-05-03T09:05:35","date_gmt":"2025-05-03T02:05:35","guid":{"rendered":"https:\/\/unair.ac.id\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\/"},"modified":"2025-05-03T09:05:35","modified_gmt":"2025-05-03T02:05:35","slug":"review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis","status":"publish","type":"post","link":"https:\/\/unair.ac.id\/en\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\/","title":{"rendered":"Review: Application of Polysaccharide Polymer Combination in Microsphere Delivery System for Anti-Tuberculosis"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><\/p>\n\n<p class=\"wp-block-paragraph\">Tuberculosis is still a health problem both in Indonesia and in the world and is one of the leading causes of death. Unfortunately, the first-line OAT therapy that is currently recommended in Indonesia has some limitations, namely requiring a long duration of treatment and starting to find cases of resistance in its use. <\/p>\n\n<p class=\"wp-block-paragraph\">Drug Delivery System is one of the solutions to this problem, as a formulation or system that is able to mediate the delivery of therapeutic substances in the body to increase therapeutic effects, reduce drug side effects, increase bioavailability and improve patient compliance. <\/p>\n\n<p class=\"wp-block-paragraph\">Therefore, in this review we will review the polysaccharide polymers used as microsphere delivery systems as anti-tubeculosis treatment. The review of this article was made using the library research method obtained through Google Scholar, PubMed, Scopus, NCBI, Elsevier with the keywords &#8220;Drug Delivery Pulmonary&#8221;, &#8220;Polysaccharide Polymer for Pulmonary&#8221;, &#8220;Chitosan Polymer&#8221;, &#8220;Sodium Alginate Polymer&#8221;, &#8220;Carrageenan Polymer&#8221;, &#8220;Pectin Polymer&#8221;, &#8220;Antibiotics Chitosan-Na.Alginate Pulmonary&#8221;, &#8220;Antibiotics Chitosan-Pectin Antibiotics&#8221;, &#8220;Antibiotics Na.Alginate \u2013 Pulmonary Carrageenan&#8221;, &#8220;Antibiotics for Tuberculosis&#8221;, &#8220;Drug Delivery for AntiTuberculosis&#8221;. <\/p>\n\n<p class=\"wp-block-paragraph\">The use of polymer combination is an option in order to complement the shortcomings of each of the other polymers, then it can produce controlled-release drugs, which have the advantage of reducing the frequency of dosing, reducing drug side effects, increasing the level of patient compliance which can certainly be a solution for the development of anti-tuberculosis drugs.<\/p>\n\n<p class=\"wp-block-paragraph\">Author: Dewi Melani Hariyadi<br\/>Details can be accessed on the link below:<br\/><a href=\"https:\/\/ejchem.journals.ekb.eg\/article_356627_6eae377f4db62f56664b7bb92210af71.pdf\">https:\/\/ejchem.journals.ekb.eg\/article_356627_6eae377f4db62f56664b7bb92210af71.pdf<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tuberculosis is still a health problem both in Indonesia and in the world and is one of the leading causes of death. Unfortunately, the first-line OAT therapy that is currently recommended in Indonesia has some limitations, namely requiring a long duration of treatment and starting to find cases of resistance in its use. Drug Delivery [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":343185,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[896,883],"tags":[892,893],"class_list":["post-351152","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-article","category-scientific-article-en","tag-aip-en-2","tag-aip-dosen-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Review: Application of Polysaccharide Polymer Combination in Microsphere Delivery System for Anti-Tuberculosis - Universitas Airlangga<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unair.ac.id\/en\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Review: Application of Polysaccharide Polymer Combination in Microsphere Delivery System for Anti-Tuberculosis - Universitas Airlangga\" \/>\n<meta property=\"og:description\" content=\"Tuberculosis is still a health problem both in Indonesia and in the world and is one of the leading causes of death. Unfortunately, the first-line OAT therapy that is currently recommended in Indonesia has some limitations, namely requiring a long duration of treatment and starting to find cases of resistance in its use. Drug Delivery [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/unair.ac.id\/en\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\/\" \/>\n<meta property=\"og:site_name\" content=\"Universitas Airlangga\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-03T02:05:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/unair.ac.id\/wp-content\/uploads\/2025\/02\/penyebab-tbc-yang-perlu-anda-ketahui1-1.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1198\" \/>\n\t<meta property=\"og:image:height\" content=\"629\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"unairnews\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"unairnews\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\\\/\"},\"author\":{\"name\":\"unairnews\",\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/#\\\/schema\\\/person\\\/d502c9ade4bcde7da8dd0fca6cc0deb0\"},\"headline\":\"Review: Application of Polysaccharide Polymer Combination in Microsphere Delivery System for Anti-Tuberculosis\",\"datePublished\":\"2025-05-03T02:05:35+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\\\/\"},\"wordCount\":267,\"publisher\":{\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/unair.ac.id\\\/wp-content\\\/uploads\\\/2025\\\/02\\\/penyebab-tbc-yang-perlu-anda-ketahui1-1.webp\",\"keywords\":[\"AIP\",\"AIP Dosen\"],\"articleSection\":[\"scientific article\",\"Scientific Article\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\\\/\",\"url\":\"https:\\\/\\\/unair.ac.id\\\/en\\\/review-application-of-polysaccharide-polymer-combination-in-microsphere-delivery-system-for-anti-tuberculosis\\\/\",\"name\":\"Review: Application of Polysaccharide Polymer Combination in Microsphere Delivery System for Anti-Tuberculosis - 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