{"id":376997,"date":"2025-11-27T15:03:45","date_gmt":"2025-11-27T08:03:45","guid":{"rendered":"https:\/\/unair.ac.id\/unair-alumna-advances-osteoporosis-cell-model-earns-loreal-unesco-fwis-honor\/"},"modified":"2025-11-27T16:01:32","modified_gmt":"2025-11-27T09:01:32","slug":"unair-alumna-advances-osteoporosis-cell-model-earns-loreal-unesco-fwis-honor","status":"publish","type":"post","link":"https:\/\/unair.ac.id\/en\/unair-alumna-advances-osteoporosis-cell-model-earns-loreal-unesco-fwis-honor\/","title":{"rendered":"UNAIR alumna advances osteoporosis cell model, earns L\u2019Or\u00e9al\u2013UNESCO FWIS honor"},"content":{"rendered":"\n

UNAIR NEWS<\/strong> \u2014 Osteoporosis remains a major global health issue affecting quality of life, particularly among women. The condition stems from an imbalance between osteoblasts, the cells that build bone, and osteoclasts, the cells that break it down. Current therapies still fall short of fully restoring bone health. Confronted with this challenge, Dr. Maria Apriliani Gani, an alumna of the Master to Doctoral Education Scholarship Programme for Excellent Scholars (PMDSU) program UNAIR\u2019s Faculty of Pharmacy, pursued a rigorous research path that ultimately earned her the 2025 L\u2019Or\u00e9al\u2013UNESCO For Women in Science (FWIS) Award.<\/p>\n\n

Research model<\/strong><\/h5>\n\n

The young UNAIR PhD graduate developed a cellular model designed to replicate osteoporotic conditions. Her model provides a more biologically relevant platform for drug screening compared to existing testing methods.<\/p>\n\n

\u201cThis model is essentially a dual-cell culture system featuring osteoblasts and osteoclasts. It mirrors the osteoporosis environment found in human bone. We hope it will eventually serve as an alternative to animal testing in osteoporosis research,\u201d Dr. Gani explained.<\/p>\n

\n
\"Dr.
Dr. Maria Apriliani Gani, PMDSU UNAIR alumna (Photo: By courtesy)<\/figcaption><\/figure><\/div>\n

She also incorporated an integrated in vitro\u2013in silico approach to accelerate the discovery of bioactive metabolites from Indonesian medicinal plants. Based on her initial predictions, several local plants show promising anti-osteoporosis potential.<\/p>\n\n

\u201cIn this project, I collaborated with a professor from UI\u2019s Faculty of Pharmacy to characterize bioactive metabolites and strengthen the herbal-medicine component. Using the cellular model I developed, we can assess how candidate plants enhance bone formation while inhibiting osteoclast activity,\u201d she said.<\/p>\n\n

Impact and challenges<\/strong><\/h5>\n\n

Dr. Gani\u2019s research holds meaningful implications for women, particularly those at highest risk of post-menopausal osteoporosis. Her work may help lay the groundwork for safer, plant-based therapies. It also contributes to faster, more effective diagnostic and drug-screening tools, ultimately improving the well-being of older women.<\/p>\n\n

She acknowledged that, despite her youth and limited professional experience, impactful research demands strong teamwork and complementary expertise. \u201cThat\u2019s why I must be proactive in collaborating with other researchers and in seeking partners, whether final-year students or research assistants, who are interested in working with me,\u201d she said.<\/p>\n\n

She added that UNAIR provided her with a strong foundation in critical thinking, discipline, and lifelong learning. She also offered a message for UNAIR students and early-career researchers: \u201cTake full advantage of every opportunity you have. Don\u2019t be afraid to dream big, don\u2019t hesitate to try new things, and never stop learning.\u201d<\/p>\n\n

Author: Adinda Octavia Setiowati<\/p>\n\n

Editor: Yulia Rohmawati<\/p>\n","protected":false},"excerpt":{"rendered":"

UNAIR NEWS \u2014 Osteoporosis remains a major global health issue affecting quality of life, particularly among women. The condition stems from an imbalance between osteoblasts, the cells that build bone, and osteoclasts, the cells that break it down. Current therapies still fall short of fully restoring bone health. Confronted with this challenge, Dr. Maria Apriliani […]<\/p>\n","protected":false},"author":79,"featured_media":376981,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4648,9067,50,4554],"tags":[14707],"class_list":["post-376997","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-alumni-en","category-alumni-news","category-news-en-2","category-news","tag-news-en-3"],"yoast_head":"\nUNAIR alumna advances osteoporosis cell model, earns L\u2019Or\u00e9al\u2013UNESCO FWIS honor - Universitas Airlangga Official Website<\/title>\n<meta name=\"description\" content=\"An alumna pursued a rigorous research path that ultimately earned her the 2025 L\u2019Or\u00e9al\u2013UNESCO For Women in Science (FWIS) Award.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unair.ac.id\/en\/unair-alumna-advances-osteoporosis-cell-model-earns-loreal-unesco-fwis-honor\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"UNAIR alumna advances osteoporosis cell model, earns L\u2019Or\u00e9al\u2013UNESCO FWIS honor - 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