{"id":382661,"date":"2025-12-31T10:49:47","date_gmt":"2025-12-31T03:49:47","guid":{"rendered":"https:\/\/unair.ac.id\/fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate\/"},"modified":"2025-12-31T10:49:47","modified_gmt":"2025-12-31T03:49:47","slug":"fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate","status":"publish","type":"post","link":"https:\/\/unair.ac.id\/en\/fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate\/","title":{"rendered":"FKG lecturer promotes downstream development of bioactive biphasic calcium phosphate"},"content":{"rendered":"\n

UNAIR NEWS<\/strong> \u2013 Research in dentistry should move beyond academic publication and lead to real-world application. That principle guides Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), a faculty member of Faculty of Dental Medicine (FKG), Universitas Airlangga<\/a> (UNAIR), who has advanced the development of a biphasic calcium phosphate (BCP)\u2013based bone filler toward downstream utilization.<\/p>\n\n

Prof. Wahyuningrum is currently overseeing several research initiatives aimed at downstream implementation. One of her main projects focuses on developing a BCP-based bone filler combined with stem cell\u2019s derived conditioned medium. The combination is designed to enhance osteogenesis, or new bone formation.<\/p>\n\n

Advantages of BCP<\/strong><\/h5>\n\n

According to Prof. Wahyuningrum, the innovation is driven by Indonesia\u2019s continued reliance on imported medical materials. Through BCP development, she seeks to produce a domestically developed research output that is not only competitive but also offers improved biological performance. <\/p>\n\n

\u201cOur goal is for BCP combined with conditioned medium to demonstrate stronger osteogenic capability than materials without this combination,\u201d she said.<\/p>\n\n

\"Prof.
Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), lecturer at FKG UNAIR. (Photo: By courtesy)\n<\/figcaption><\/figure>\n\n

She added that this approach remains relatively uncommon, as most commercially available biomaterials still rely on single-material compositions. The strength of this innovation lies in its dual function: supporting bone regeneration while also providing antibacterial properties. This is particularly relevant in dental practice, where bone damage is often caused by root canal infections involving microbial invasion.<\/p>\n\n

Toward practical application<\/strong><\/h5>\n\n

Prof. Wahyuningrum noted that transforming research into a usable product involves several challenges. One of the main hurdles was combining BCP with conditioned medium, a method that is not yet widely adopted. Through targeted research collaboration, however, these challenges were successfully addressed, resulting in an innovation that optimizes the biological environment for stem cells.<\/p>\n\n

Given the high demand for bone graft materials, Prof. Wahyuningrum hopes the product can soon enter the pre-commercial phase. Her team has begun exploring collaboration with PT Hexa Dental Indonesia, a dental materials manufacturing company, to assess opportunities for scaling the product for industrial use. <\/p>\n\n

\u201cResearch should not stop at a single study, but should reach a point where it can be applied. If we want research to truly benefit society, it must be brought into downstream processes that deliver real value to the public,\u201d she said.<\/p>\n\n

Author: Adinda Octavia Setiowati<\/p>\n\n

Editor: Yulia Rohmawati<\/p>\n","protected":false},"excerpt":{"rendered":"

UNAIR NEWS \u2013 Research in dentistry should move beyond academic publication and lead to real-world application. That principle guides Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), a faculty member of Faculty of Dental Medicine (FKG), Universitas Airlangga (UNAIR), who has advanced the development of a biphasic calcium phosphate (BCP)\u2013based bone filler toward downstream utilization. Prof. […]<\/p>\n","protected":false},"author":2,"featured_media":382562,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[894,857,856],"tags":[836],"class_list":["post-382661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovation","category-news-en-2","category-news-en","tag-news-en-3"],"yoast_head":"\nFKG lecturer promotes downstream development of bioactive biphasic calcium phosphate - 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