
{"id":382661,"date":"2025-12-31T10:49:47","date_gmt":"2025-12-31T03:49:47","guid":{"rendered":"https:\/\/unair.ac.id\/fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate\/"},"modified":"2026-01-02T17:21:41","modified_gmt":"2026-01-02T10:21:41","slug":"fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate","status":"publish","type":"post","link":"https:\/\/unair.ac.id\/en\/fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate\/","title":{"rendered":"FKG lecturer promotes downstream development of bioactive biphasic calcium phosphate"},"content":{"rendered":"\n<p><strong>UNAIR NEWS<\/strong> \u2013 Research in dentistry should move beyond academic publication and lead to real-world application. That principle guides Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), a faculty member of Faculty of Dental Medicine (FKG), <a href=\"http:\/\/unair.ac.id\">Universitas Airlangga<\/a> (UNAIR), who has advanced the development of a biphasic calcium phosphate (BCP)\u2013based bone filler toward downstream utilization.<\/p>\n\n<p>Prof. Wahyuningrum is currently overseeing several research initiatives aimed at downstream implementation. One of her main projects focuses on developing a BCP-based bone filler combined with stem cell\u2019s derived conditioned medium. The combination is designed to enhance osteogenesis, or new bone formation.<\/p>\n\n<h5 class=\"wp-block-heading has-black-color has-text-color has-link-color wp-elements-d26745afa705e0bddc95ce9e42214f9b\"><strong>Advantages of BCP<\/strong><\/h5>\n\n<p>According to Prof. Wahyuningrum, the innovation is driven by Indonesia\u2019s continued reliance on imported medical materials. Through BCP development, she seeks to produce a domestically developed research output that is not only competitive but also offers improved biological performance. <\/p>\n\n<p>\u201cOur goal is for BCP combined with conditioned medium to demonstrate stronger osteogenic capability than materials without this combination,\u201d she said.<\/p>\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"763\" height=\"1024\" src=\"https:\/\/unair.ac.id\/wp-content\/uploads\/2025\/12\/Prof-Dian-Wahyuningrum-763x1024.jpg\" alt=\"Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), lecturer at FKG UNAIR.\" class=\"wp-image-382559\" style=\"width:337px;height:auto\" srcset=\"https:\/\/unair.ac.id\/wp-content\/uploads\/2025\/12\/Prof-Dian-Wahyuningrum-763x1024.jpg 763w, https:\/\/unair.ac.id\/wp-content\/uploads\/2025\/12\/Prof-Dian-Wahyuningrum-223x300.jpg 223w, https:\/\/unair.ac.id\/wp-content\/uploads\/2025\/12\/Prof-Dian-Wahyuningrum.jpg 765w\" sizes=\"(max-width: 763px) 100vw, 763px\" \/><figcaption class=\"wp-element-caption\">Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), lecturer at FKG UNAIR. (Photo: By courtesy)\n<\/figcaption><\/figure>\n\n<p>She added that this approach remains relatively uncommon, as most commercially available biomaterials still rely on single-material compositions. The strength of this innovation lies in its dual function: supporting bone regeneration while also providing antibacterial properties. This is particularly relevant in dental practice, where bone damage is often caused by root canal infections involving microbial invasion.<\/p>\n\n<h5 class=\"wp-block-heading has-black-color has-text-color has-link-color wp-elements-8c3d93b6356c3cfbee9d84f5203a02db\"><strong>Toward practical application<\/strong><\/h5>\n\n<p>Prof. Wahyuningrum noted that transforming research into a usable product involves several challenges. One of the main hurdles was combining BCP with conditioned medium, a method that is not yet widely adopted. Through targeted research collaboration, however, these challenges were successfully addressed, resulting in an innovation that optimizes the biological environment for stem cells.<\/p>\n\n<p>Given the high demand for bone graft materials, Prof. Wahyuningrum hopes the product can soon enter the pre-commercial phase. Her team has begun exploring collaboration with PT Hexa Dental Indonesia, a dental materials manufacturing company, to assess opportunities for scaling the product for industrial use. <\/p>\n\n<p>\u201cResearch should not stop at a single study, but should reach a point where it can be applied. If we want research to truly benefit society, it must be brought into downstream processes that deliver real value to the public,\u201d she said.<\/p>\n\n<p>Author: Adinda Octavia Setiowati<\/p>\n\n<p>Editor: Yulia Rohmawati<\/p>\n","protected":false},"excerpt":{"rendered":"<p>UNAIR NEWS \u2013 Research in dentistry should move beyond academic publication and lead to real-world application. That principle guides Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), a faculty member of Faculty of Dental Medicine (FKG), Universitas Airlangga (UNAIR), who has advanced the development of a biphasic calcium phosphate (BCP)\u2013based bone filler toward downstream utilization. Prof. [&hellip;]<\/p>\n","protected":false},"author":79,"featured_media":382562,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4654,50,4554],"tags":[14707],"class_list":["post-382661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovation","category-news-en-2","category-news","tag-news-en-3"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>FKG lecturer promotes downstream development of bioactive biphasic calcium phosphate - Universitas Airlangga Official Website<\/title>\n<meta name=\"description\" content=\"Prof. Dian Agustin Wahyuningrum, drg., Sp.KG., Subsp.KE(K), a faculty member of Faculty of Dental Medicine (FKG), Universitas Airlangga (UNAIR), has advanced the development of a biphasic calcium phosphate (BCP)\u2013based bone filler toward downstream utilization.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/unair.ac.id\/en\/fkg-lecturer-promotes-downstream-development-of-bioactive-biphasic-calcium-phosphate\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FKG lecturer promotes downstream development of bioactive biphasic calcium phosphate - 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