Periodontitis affects skeletal muscle metabolism through an increase in proinflammatory cytokines
Periodontitis is an inflammatory disease characterized by inflammation of the soft tissues and the periodontal ligament and also alveolar bone damage. Periodontal disease is mainly caused by infection from gram-negative bacteria such as Porphyromonas gingivalis (P.gingivalis) and bacteroide. Inflammation will triggered by the interaction between these bacteria and the host’s immune systems, causing damage to […]
Testing the determining factors of knowledge sharing behavior
In today’s information-based economy, knowledge is considered as a critical and effective resource for assisting businesses in establishing departmental synergies, accelerating innovation, providing value to customers, and increasing revenue through market growth. Knowledge sharing behavior is defined as individual behavior that pertains to the exchange of information, experience, ideas, and skills with other individuals or […]
Effect of probiotic and Moringa Oleifera extract on performance, carcass yield, and mortality of Peking duck
Duck is one of the livestock commodities that have a high economic value. This is related to the endurance of the duck body and the ability of adaptation is quite high. The production of duck meat in Indonesia is always increasing. In 2017, the duck meat production was 42,318.86 tons, and then, it increased to […]
Bioactive compounds from mangosteen as an antiviral agent against SARSCoV-2
Coronavirus 2 (SARS‑CoV‑2) is the virus that causes COVID-19 which is responsible for respiratory illness infection in humans. The virus was first identified in China in 2019 and later spread to other countries worldwide. This study aims to identify the bioactive compounds from mangosteen (Garcinia mangostana L.) as an antiviral agent via dual inhibitor mechanisms […]
Development of population pharmacokinetics model of isoniazid in patients with tuberculosis
Tuberculosis (TB) remains one of the top 10 causes of death worldwide and is ranked higher than human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). TB affects more than 10 million people worldwide and causes 1.4 million deaths annually, according to the World Health Organization (WHO) TB report published in 2019. The burden of disease is […]
Identification of CF mutations and clinical symptoms in CBAVD patients
CBAVD has an incidence of 1-2 percent in men who experience infertility, followed by damage to various ducts. This condition is caused by a lack of sperm count due to a natural defect caused by an autosomal recessive genetic disorder. This is sometimes referred to as an infectious disease. Based on several studies, the CFTR […]
Prevalence of extended-spectrum ß-lactamase-producing Escherichia coli in companion dogs
Extended-spectrum β-lactamase (ESBL) is an enzyme produced by Gram-negative bacteria (family Enterobacteriaceae), which is a threat to health in the fields of human and veterinary medicine globally. The production of this enzyme by these bacteria confers resistance to cephalosporin and monobactam, but not to cephamycin or carbapenem, and it is inhibited by β-lactamase inhibitors such […]
Potential marker for diagnosis and screening of iron deficiency anemia in children
Iron plays a role in multiple physiological functions, naming oxygen transport, gene regulation, DNA synthesis, DNA repair, and brain function. Depletion of and inability to use iron disturbs these pathways and causes multiple morbidities. Three main body iron compartments describe iron status inadequacy: iron stores, transport iron, and functional iron. Anemia resulting from iron deficiency […]
The importance of dental age estimation methods for individual identification in Indonesia
Indonesia is an archipelagic country located in the ring of fire area. It is bordered by tectonically active zones characterized by intense seismicity and volcanism. This geographic condition is often associated with the high risk of disaster in Indonesia. Many natural disasters such as earthquakes, volcanic eruptions, tsunamis, and liquefaction have happened in Indonesia in […]
Therapeutic plasma exchange and the risk of COVID-19 mortality
Since first reported in December 2019, coronavirus disease 2019 (COVID-19) has become an unresolved global pandemic. The treatment of critically ill COVID-19 patients remains a serious issue. Patients critically ill with COVID-19 have been widely reported to have a poor prognosis, and theory reveals that cytokine storm might underlie this mechanism. No study has found […]
Natural killer cell in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with acute periodic recurrences affecting multiple organ systems, characterized by loss of tolerance to nucleic acids, and has a wide variety of clinical manifestations, leading to potentially lifethreatening complications. SLE also can affect the innate and adaptive immune system. Natural Killer cells (NK) are lymphocytes in […]
Combination of multivitamins and sunlight for bone health
One of the most common metabolic conditions worldwide, both in developed and developing countries, is vitamin D deficiency. Vitamin D deficiency in Asians of all ages mostly occur. It is an essential nutrient for optimal health and bone growth. It has been found that 90% needed for humans comes from exposure to the sun UV-B […]